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Parasite Specific Antibody Increase Induced by an Episode of Acute P. falciparum Uncomplicated Malaria

Kaddumukasa, M; Lwanira, C; Lugaajju, A; Katabira, E; Persson, K. E. M.; Wahlgren, M; Kironde, Fred (2015)

Introduction There is no approved vaccine for malaria, and precisely how human antibody responses to malaria parasite components and potential vaccine molecules are developed and maintained remains poorly defined. In ...

Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens

Reddy, S. B.; Anders, R. F.; Cross, N; Mueller, I; Senn, N; Stanisic, D. I.; Siba, P. M.; Wahlgren, M; Kironde, Fred; Beeson, J. G.; Persson, K. E. M (2015)

Background: Malaria is a major global cause of deaths and a vaccine is urgently needed. Results: We have employed the P. falciparum merozoite antigens MSP2-3D7/FC27 and AMA1, used them in ELISA, and coupled them in ...